In 1976 Bucaille published his book, The Bible, The Qur'an and Science which argued that the Quran contains no statements contradicting established scientific facts.[4] Bucaille argued that the Quran is in agreement with scientific facts, while the Bible is not. He states that in Islam, science and religion have always been “twin sisters” (vii). According to Bucaille, there are monumental errors of science in the Bible and not a single error in the Quran. Bucaille's belief is that the Quran's descriptions of natural phenomena make it compatible with modern science. Bucaille concludes that the Quran is the Word of God.
Bucaille argues that the Old Testament has been distorted because of numerous translations and corrections as it was transmitted orally. He highlights, in his words, “numerous disagreements and repetitions”, in the Old Testament and the Gospels. In his analysis, Bucaille claims he makes use of many propositions of Biblical criticism, such as the documentary hypothesis.